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Reynolds research featured in BBC report (It's Happening, November 7, 2007) Sheep offer clues to small babies (September 19, 2007) Reynolds invited to speak at joint NIH-NRI workshop (March 2007) Hafez participating in CNP study (March 2007) Agriculture faculty, staff honored (December 2006) Reynolds returns from collaborative research trip to Italy (December 2006)
For months, doctoral candidate Pawel Borowicz has spent hours each week in a Hultz Hall laboratory, laboring over a computer image. The picture, composed of lurid pools of fuchsia and blue, resembles a Doppler radar map gone bad. Like what would happen if a blizzard-spewing tornado cleaved right through the heart of a hurricane... To continue reading this article, click here. ND INBRE PRESENTATIONS CNP faculty and staff have presented several lectures as part of an ongoing series of biological research presentations with the ND INBRE. To access those presentations, please click on the following links:
The link for the enitre ND INBRE Biology Core Lecture Series is http://ndinbre.org/Biology/presentations.htm. NDSU'S BOROWICZ WINS SCIENCE HONOR
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here. ____________________________________________________________ Research over the last 75 years has demonstrated that maternal nutrition has a dramatic impact on birth weights and long-term health and productivity in humans and animals. More importantly, the impact of nutrition, especially during the first half of pregnancy, cannot be overcome by providing adquate nutrition during the latter half of pregnancy. In spite of this, nutritional levels during the first half of prenancy often are only marginal, with the focus being on adequate nutrition later in pregnancy. In addition, in animals and humans, offspring whose mothers were subjected to either under- or overnutrition exhibit defective function of a variety of organ systems throughout their lifespan, as reflected by a wide range of metabolic, endocrine, and immune system disorders, including poor growth, poor fertility, high blood pressure, heart disease, stroke, and diabetes. Thus, we inadvertently may be impacting the long-term health and productivity of offspring by providing only marginal nutrition during the first half of pregnancy. In humans, as well as in other mammalian species including livestock, the first pregnancy often occurs during adolescence, while the mother is still growing. Although the effects of undernutrition in adolescent pregnancies have not been well studied, overnutrition results in a 40-50% reduction in placental and birth weights. These observatios have important implications for both human health and animal production. The impact of nutrition on compromised pregnancies, such as those which commonly occur in aged mothers, remains largely unexplored. Likewise, although fetal and maternal genotypes have a dramatic influence on fetal and placental growth and development, the interaction of nutrition with genotype remains largely unknown. Moreover, although the number of fetuses occupying the pregnant uterus has a large impact on placental function and birth weight, the role of nutrition in pregnancies with multiple fetuses remains largely unexplored. CNP investigators are currently pursuing all of these relatively unexplored research topics, especially as related to maternal nutrition. We also are beginning to investigate nutritional impacts on the offspring from these compromised pregnancies. |
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